Publikationen

Eine Auswahl unserer Publikationen zu den Themen Placebo- und Noceboantwort:

Benson S, Theysohn N, Kleine-Borgmann J, Rebernik L, Icenhour A, Elsenbruch S.
Positive Treatment Expectations Shape Perceived Medication Efficacy in a Translational Placebo Paradigm for the Gut-Brain Axis.
Front Psychiatry. 2022;13:824468.

Schmidt K, Berding T, Kleine-Borgmann J, Engler H, Holle-Lee D, Gaul C, Bingel U.
The beneficial effect of positive treatment expectations on pharmacological migraine prophylaxis.
Pain. 2022;163(2):e319-e327.

Haas JW, Bender FL, Ballou S, Kelley JM, Wilhelm M, Miller FG, Rief W, Kaptchuk TJ.
Frequency of Adverse Events in the Placebo Arms of COVID-19 Vaccine Trials: A Systematic Review and Meta-analysis.
JAMA Netw Open. 2022;5(1):e2143955.

Hadamitzky M, Schedlowski M.
Harnessing associative learning paradigms to optimize drug treatment.
Trends Pharmacol Sci. 2022;S0165-6147(22)00052-9. doi: 10.1016/j.tips.2022.03.002.

Pfaar O, Agache I, Bergmann KC, Bindslev-Jensen C, Bousquet J, Creticos PS, Devillier P, Durham SR, Hellings P, Kaul S, Kleine-Tebbe J, Klimek L, Jacobsen L, Jutel M, Muraro A, Papadopoulos NG, Rief W, Scadding GK, Schedlowski M, Shamji MH, Sturm G, van Ree R, Vidal C, Vieths S, Wedi B, Gerth van Wijk R, Frew AJ.
Placebo effects in allergen immunotherapy-An EAACI Task Force Position Paper.
Allergy. 2021;76(3):629-647.

Lückemann L, Hetze S, Hörbelt T, Jakobs M, Schedlowski M, Hadamitzky M.
Incomplete reminder cues trigger memory reconsolidation and sustain learned immune responses.
Brain Behav Immun. 2021;95:115-121.

Sondermann W, Reinboldt-Jockenhöfer F, Dissemond J, Pfaar O, Bingel U, Schedlowski M.
Effects of Patients' Expectation in Dermatology: Evidence from Experimental and Clinical Placebo Studies and Implications for Dermatologic Practice and Research.
Dermatology. 2021;237(6):857-871.

Evers AWM, Colloca L, Blease C, Gaab J, Jensen KB, Atlas LY, Beedie CJ, Benedetti F, Bingel U, Büchel C, Bussemaker J, Colagiuri B, Crum AJ, Finniss DG, Geers AL, Howick J, Klinger R, Meeuwis SH, Meissner K, Napadow V, Petrie KJ, Rief W, Smeets I, Wager TD, Wanigasekera V, Vase L, Kelley JM, Kirsch I, Consortium of Placebo Experts.
What Should Clinicians Tell Patients about Placebo and Nocebo Effects? Practical Considerations Based on Expert Consensus.
Psychother Psychosom. 2021;90(1):49-56.

Salzmann S, Euteneuer F, Laferton JAC, Shedden-Mora MC, Schedlowski M, Moosdorf R, Rief W.
IL-8 and CRP moderate the effects of preoperative psychological interventions on postoperative long-term outcomes 6 months after CABG surgery - The randomized controlled PSY-HEART trial.
Brain Behav Immun. 2021;91:202-211.

Schlitt F, Schmidt K, Merz CJ, Wolf OT, Kleine-Borgmann J, Elsenbruch S, Wiech K, Forkmann K, Bingel U.
Impaired pain-related threat and safety learning in patients with chronic back pain.
Pain. 2021. Online ahead of print.

Schmidt K, Kleine-Borgmann J, Holle-Lee D, Gaul C, Bingel U.
Impact of a 12-week open-label placebo treatment on headache days in episodic and chronic migraine: a study protocol for a parallel-group, multicentre, randomised controlled trial.
BMJ Open. 2021;11(6):e045969.

Asan L, Benson S, Bingel U.
[Primum nil nocere: The nocebo effect in clinical practice].
MMW Fortschr Med. 2021;163(15):56-61.

Zunhammer M, Spisák T, Wager TD, Bingel U; Placebo Imaging Consortium.
Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data.
Nat Commun. 2021;12(1):1391.

Haas JW, Rief W, Glombiewski J A, Winkler A, & Doering BK.
Expectation-induced placebo effect on acute sadness in women with major depression: An experimental investigation.
Journal of Affective Disorders. 2020; 274:920-928.

Hansen E, Zech N, Benson S.
[Nocebo, informed consent and doctor-patient communication].
Nervenarzt. 2020;91(8):691-699.

Lückemann L, Stangl H, Straub RH, Schedlowski M, Hadamitzky M.
Learned Immunosuppressive Placebo Response Attenuates Disease Progression in a Rodent Model of Rheumatoid Arthritis.
Arthritis Rheumatol. 2020;72(4):588-597.

Hadamitzky M, Lückemann L, Pacheco-López G, Schedlowski M.
Pavlovian Conditioning of Immunological and Neuroendocrine Functions.
Physiol Rev. 2020;100(1):357-405. doi: 10.1152/physrev.00033.2018. Epub 2019 Aug 22.PMID: 31437089 Free article. Review.

Schemer L, Rief W, Glombiewski JA.
Treatment Expectations Towards Different Pain Management Approaches: Two Perspectives.
J Pain Res. 2020;13:1725-1736.

Bingel U.
Placebo 2.0: the impact of expectations on analgesic treatment outcome.
Pain. 2020;161.

Spisak T, Kincses B, Schlitt F, Zunhammer M, Schmidt-Wilcke T, Kincses ZT, Bingel U.
Pain-free resting-state functional brain connectivity predicts individual pain sensitivity.
Nat Commun. 2020;11(1):187.

Kube T, Schwarting R, Rozenkrantz L, Glombiewski JA, & Rief W.
Distorted Cognitive Processes in Major Depression: A Predictive Processing Perspective.
Biological Psychiatry. 2020; 87:388-398.

Kube T, Rief W, Vivell MB, Schafer NL, Vermillion T, Korfer K, & Glombiewski JA.
Deceptive and Nondeceptive Placebos to Reduce Pain An Experimental Study in Healthy Individuals.
Clinical Journal of Pain. 2020; 36:68-79.

Rebstock L, Schäfer LN, Kube T, Ehmke V, Rief W.
Placebo prevents rumination: An experimental study.
Journal of Affective Disorders. 2020; 274:1152-60.

Riecke J, Rief W, Vlaeyen JWS, & Glombiewski JA.
Generalizability of harm and pain expectations after exposure in chronic low back pain patients.
European Journal of Pain. 2020; 24:1495-1504.

Rief W. The role of placebo and nocebo mechanisms in depressive diseases and their treatment. Nervenarzt. 2020; 91: 675-683.

Hadamitzky M, Lückemann L, Pacheco-López G, Schedlowski M.
Pavlovian Conditioning of Immunological and Neuroendocrine Functions.
Physiol Rev. 2020;100:357-405

Spisak T, Kincses B, Schlitt F, Zunhammer M, Schmidt-Wilcke T, Kincses ZT, Bingel U.
Pain-free resting-state functional brain connectivity predicts individual pain sensitivity.
Nat Commun. 2020;11(1):187.

Jockenhöfer F, Knust C, Benson S, Schedlowski M, Dissemond J.
Influence of placebo effects on quality of life and wound healing in patients with chronic venous leg ulcers.
J Dtsch Dermatol Ges. 2020;18(2):103-109.

Elsenbruch S, Roderigo T, Enck P, Benson S.
Can a Brief Relaxation Exercise Modulate Placebo or Nocebo Effects in a Visceral Pain Model?
Front Psychiatry. 2019;10:144.

Lückemann L, Stangl H, Straub RH, Schedlowski M, Hadamitzky M.
Learned immunosuppressive placebo response attenuates disease progression in a rodent model of rheumatoid arthritis.
Arthritis Rheumatol. 2019. Epub ahead of print

Kleine-Borgmann J, Schmidt K, Hellmann A, Bingel U.
Effects of open-label placebo on pain, functional disability, and spine mobility in patients with chronic back pain: a randomized controlled trial.
Pain. 2019;160(12):2891-2897.

Benson S, Hagen S, Hoffmann O, Pasler A, Bingel U, Schedlowski M, Peters J, Elsenbruch S, Frey UH.
Can a brief psychological expectancy intervention improve postoperative pain? A randomized, controlled trial in breast cancer patients.
Pain.2019;1562-1571.

Lückemann L, Unteroberdörster M, Martinez Gomez E, Schedlowski M, Hadamitzky M.
Behavioral conditioning of anti-proliferative and immunosuppressive properties of the mTOR inhibitor rapamycin.
Brain Behav Immun. 2019;326-331.

Petrie KJ, Rief W.
Psychobiological Mechanisms of Placebo and Nocebo Effects: Pathways to Improve Treatments and Reduce Side Effects.
Annu Rev Psychol. 2019;70:599-625.

Zunhammer M, Bingel U, Wager TD; Placebo Imaging Consortium.
Placebo Effects on the Neurologic Pain Signature: A Meta-analysis of Individual Participant Functional Magnetic Resonance Imaging Data.
JAMA Neurol. 2018;75:1321-1330.

Evers AWM, Colloca L, Blease C, Annoni M, Atlas LY, Benedetti F, Bingel U, Büchel C, Carvalho C, Colagiuri B, Crum AJ, Enck P, Gaab J, Geers AL, Howick J, Jensen KB, Kirsch I, Meissner K, Napadow V, Peerdeman KJ, Raz A, Rief W, Vase L, Wager TD, Wampold BE, Weimer K, Wiech K, Kaptchuk TJ, Klinger R, Kelley JM.
Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus.
Psychother Psychosom. 2018;87:204-210.

Kube T, Glombiewski JA, Rief W.
Using Different Expectation Mechanisms to Optimize Treatment of Patients With Medical Conditions: A Systematic Review.
Psychosom Med. 2018;80:535-543.

Kirchhof J, Petrakova L, Brinkhoff A, Benson S, Schmidt J, Unteroberdörster M, Wilde B, Kaptchuk TJ, Witzke O, Schedlowski M.
Learned immunosuppressive placebo responses in renal transplant patients.
Proc Natl Acad Sci. 2018; 115:4223-4227.

Salzmann S, Euteneuer F, Laferton JAC, Auer CJ, Shedden-Mora MC, Schedlowski M, Moosdorf R, Rief W.
Effects of Preoperative Psychological Interventions on Catecholamine and Cortisol Levels After Surgery in Coronary Artery Bypass Graft Patients: The Randomized Controlled PSY-HEART Trial.
Psychosom Med. 2017;79:806-814.

Zunhammer M, Ploner M, Engelbrecht C, Bock J, Kessner SS, Bingel U.
The effects of treatment failure generalize across different routes of drug administration.
Sci Transl Med. 2017;9(393).

Rief W, Shedden-Mora MC, Laferton JA, Auer C, Petrie KJ, Salzmann S, Schedlowski M, Moosdorf R.
Preoperative optimization of patient expectations improves long-term outcome in heart surgery patients: results of the randomized controlled PSY-HEART trial.
BMC Med. 2017;15:4.

Roderigo T, Benson S, Schöls M, Hetkamp M, Schedlowski M, Enck P, Elsenbruch S.
Effects of acute psychological stress on placebo and nocebo responses in a clinically relevant model of viseroception
Pain. 2017;1489-1498

Zunhammer M, Ploner M, Engelbrecht C, Bock J, Kessner S, Bingel U.
The effects of treatment failure generalize across different routes of drug administration
Sci Transl Med. 2017;9:393.

Enck P, Chae Y, Elsenbruch S.
Novel designs and paradigms to study the placebo responce in gastroenterology
Curr Opin Pharmacol. 2017;72-79

Nestoriuc Y, von Blanckenburg P, Schuricht F, Barsky AJ, Hadji P, Albert US, Rief W.
Is it best to expect the worst? Influence of patients' side-effect expectations on endocrine treatment outcome in a 2-year prospective clinical cohort study.
Ann Oncol. 2016;27:1909-15.

Rief W
, Barsky AJ, Bingel U, Doering BK, Schwarting R, Wöhr M, Schweiger U.
Rethinking psychopharmacotherapy: The role of treatment context and brain plasticity in antidepressant and antipsychotic interventions.
Neurosci Biobehav Rev. 2016;60:51-64.

Nestoriuc Y, von Blanckenburg P, Schuricht F, Barsky AJ, Hadji P, Albert US, Rief W.
Is it best to expect the worst? Influence of patients' side-effect expectations on endocrine treatment outcome in a 2-year prospective clinical cohort study.
Ann Oncol. 2016;1909-15.

Elsenbruch S, Enck P.
Placebo effects and their determinants in gastrointestinal disorders.
Nat Rev Gastroenterol Hepatol 2015;472-85.

Schedlowski M, Enck P, Rief W, Bingel U.
Neuro-Bio-Behavioral Mechanisms of Placebo nd Nocebo Responses: Implications for Clinical Trials and Clinical Practice.
Pharmacol Rev, 2015;697-730.

Rief W
, Glombiewski JA, Gollwitzer M, Schubö A, Schwarting R, Thorwart A.
Expectancies as core features of mental disorders.
Curr Opin Psychiatry, 2015.

Wendt L, Albring A, Benson S, Engler H, Engler A, Hinney A, Rief W, Witzke O, Schedlowski M.
Catechol-O-methyltransferase Val158Met polymorphism is associated with somatosensory amplification and nocebo responses.
PLoS One 15, 2014.

Albring A, Wendt L, Benson S, Nissen S, Yavuz Z, Engler H, Witzke O, Schedlowski M.
Preserving learned immunosuppressive placebo response: perspectives for clinical application.
Clinical Pharmacology & Therapeutics 2014;247-255.

Bingel U; For the Placebo Competence Team.
Avoiding Nocebo Effects to Optimize Treatment Outcome.
JAMA 2014.

Enck P, Bingel U, Schedlowski M, Rief W.

The placebo response in medicine: minimize, maximize or personalize.
Nature Review Drug Discovery 2013;191-204.